Overview
The goal of this observational study is to determine the urinary proteomic characteristics in women with and without ovarian cancer. The main questions it aims to answer are:
- What is the difference in urinary protein composition between patients with ovarian cancer and those without it?
- Can these differences in urinary protein composition aid in the diagnosis of ovarian cancer?
- Are urinary protein markers associated with tumor burden in urine samples from patients with ovarian cancer?
- Can urinary protein markers be used for disease surveillance in ovarian cancer patients?
Eligibility
Inclusion Criteria:
- Female patients in the gynecological ward for surgical treatment.
- Initial diagnosis of "pelvic mass" or "malignant ascites" may be considered as ovarian cancer; Or the initial diagnosis of "ovarian cyst", "hydrosalpinx", "uterine fibroids" or "uterine adenomyosis" are considered as gynecological non-malignant diseases.
- Over 18 years of age.
- Voluntary participation and signing of informed consent.
Exclusion Criteria:
- Study participants with a prior history of malignant tumors.
- Study participants with prior chronic kidney disease or renal insufficiency.
- Study participants who have received or are receiving treatment for primary disease.
- Study participants whose pathological diagnosis was not clear.
Any patient should be excluded from the study if:
- Study participants withdraw informed consent and request withdrawal.
- Study participants were unable to provide a qualified urine sample.
- There are situations in which the researcher considers it necessary to withdraw from the study.