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Sleep and Central Auditory Processing Disorder in Autism Spectrum Disorder

Sleep and Central Auditory Processing Disorder in Autism Spectrum Disorder

Recruiting
6-17 years
All
Phase N/A

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Overview

The proposed study aims to understand poor sleep as a possible cause to CAPD in children and adolescents with ASD (ASD+) compared to ASD youth without CAPD (ASD-), using both caregiver-report and objective clinician administered measures. Additionally, the study will aim to understand the complex relationship between CAPD, sleep, and other associated phenotypic features of ASD such as executive and psychiatric functioning.

Description

Participation will involve one assessment session approximating 4 hours including administration of neurocognitive and socioemotional measures by trained research staff. The research team then will determine which participants meet CAPD diagnostic criteria for both the SCAN-3 and RGDT tests and assign them to the ASD+ group. Participants not meeting these criteria will be assigned to the ASD- group. Following the assessment visit, all participants will then be asked to wear actigraphy monitors (comparable to overnight polysomnography) regularly for 14 days during nighttime sleep to objectively measure sleep quality.

Eligibility

Inclusion Criteria:

  • Have diagnosis of Autism Spectrum Disorder confirmed by the Autism Diagnostic Observation Schedule and the Social Communication Questionnaire, Lifetime Version which will be filled by the parent
  • IQ of 50 or higher on the Abbreviated Battery IQ Score

Exclusion Criteria:

  • No confirmed diagnosis of Autism Spectrum Disorder
  • History of sleep apnea
  • History of restless leg syndrome
  • History of any neurological disorders (e.g., seizures, tumors, etc.)
  • Significant substance use in the past six months
  • Inpatient hospitalization in the past three months-period

Study details
    Central Auditory Processing Disorder
    Autism Spectrum Disorder
    Sleep Disturbance

NCT06059352

Loma Linda University

16 January 2025

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