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Physiological Effects of Lung Impedance Tomography-Guided and Plat Pressure-Guided Phigh During APRV in Patients With ARDS

Physiological Effects of Lung Impedance Tomography-Guided and Plat Pressure-Guided Phigh During APRV in Patients With ARDS

Recruiting
18 years and older
All
Phase N/A
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Overview

This study aims to investigate the effects of EIT-guided and Pplat-guided Phigh settings on regional ventilation and perfusion in ARDS patients during APRV, while also examining the impact of different Phigh settings on gas exchange, respiratory mechanics, and hemodynamics.

Eligibility

Inclusion Criteria:

  • Diagnosed with ARDS according to the 2023 global new definition of ARDS.
  • Age ≥ 18 years.

Exclusion Criteria:

  • Severe chronic obstructive pulmonary disease, severe asthma, pulmonary bullae, pneumothorax, subcutaneous emphysema, mediastinal emphysema, etc. · Contraindications for EIT, such as chest wound dressing, pacemaker implantation, defibrillator use, etc.
  • Pulmonary interstitial disease.
  • Uncorrected shock of various types.
  • Intracranial hypertension.
  • Pregnant and postpartum women.

Study details
    ARDS: Acute Respiratory Distress Syndrome

NCT06696638

XiaoJing Zou,MD

15 January 2025

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