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The Collaborative Care PrTNER Study

The Collaborative Care PrTNER Study

Recruiting
15-24 years
Male
Phase N/A

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Overview

A randomized controlled trial to assess the ability of a Collaborative Care Prevention, Treatment, Navigation, Engagement, Resource (PrTNER) intervention to increase initiation of preexposure prophylaxis (PrEP) (for those at-risk for HIV) and decrease viral load (for those living with HIV) among young Black and Latino men who have sex with men (YBLMSM) aged 15 to 24 through engagement in SU treatment.

Description

The Collaborative Care (CC) PrTNER is a multi-component intervention developed by members of the research team specifically for YBLMSM aged 15 to 24 who are at-risk for or living with HIV. This model moves beyond the individual to consider the broader context in which, substance use (SU), and HIV risk are (re)produced.

Enhanced models that integrate SU treatment into HIV and PrEP primary care services (using a collaborative care approach that incorporates feedback from a psychiatrist and support from a peer coach) are needed to address the nuance of substance use in this population. We, therefore, are proposing to conduct a randomized trial to evaluate an integrated collaborative care model (CC PrTNER).

Eligibility

Inclusion Criteria:

Aim 1:

  • 15-24 years old;
  • Cisgender male;
  • Self-identified Black/African American race or Latino/Hispanic ethnicity;
  • Report prior oral/anal sex with another male;
  • At-risk for HIV (condomless anal sex or positive sexually transmitted infection (STI) in last 6 months);
  • Moderate-to-high risk SU behaviors based upon a Car, Relax, Alone, Forget, Friends, Trouble (CRAFFT) score ≥2,
  • Living in Philadelphia, PA or Baltimore, MD, and surrounding areas;
  • Able to read and write in English

Aim 2:

  • 15-24 years old;
  • Cisgender male;
  • Self-identified Black/African American race or Latino/Hispanic ethnicity;
  • Report prior oral/anal sex with another male;
  • Living with a diagnosis of HIV;
  • CRAFFT score ≥2,
  • Living in Philadelphia, PA or Baltimore, MD, and surrounding areas;
  • Able to read and write in English

Aim 3

• All randomized study participants will be included in Aim 3.

Exclusion Criteria:

Aim 2:

  • Participants will be excluded if they are:
  • Assigned female sex at birth
  • Identify as transgender
  • Outside the age criteria (<15 or >24 years old)
  • Cognitively unable to complete study requirements
  • Living outside of the two geographic areas
  • Do not screen positive for SU
  • No prior substance use history
  • No prior oral or anal sex;
  • Unable to read or write in English,
  • Plan to move in the next 12 months.

Study details
    HIV
    Substance Use Disorders
    Substance Use
    AIDS

NCT06585631

Children's Hospital of Philadelphia

3 June 2025

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