Overview
The goal of this clinical trial is to compare the perioperative parameters of femtosecond laser-assisted cataract surgery (FLACS) using two laser systems.
Participants will:
Undergo FLACS using LenSx or Z8 femtosecond laser system Visit the clinic before the operation and 1 day, 1 week, and 1 month after the operation for checkups and tests Complete clinical measurements and dry eye questionnaires
Eligibility
Inclusion Criteria:
- Chinese Han patients aged 40 years or older
- clinical diagnosis of age-related cataracts;
- underwent FLACS with insertion of a posterior chamber IOL for the first eye.
Exclusion Criteria:
- coexisting macular pathologies such as epiretinal membrane, macular hole or edema, or age-related macular degeneration. Patients with OCT scans of poor quality were excluded;
- preoperative flare of more than 15ph/ms11, ECD<2000cells/mm2 or any other corneal pathologies;
- coexisting serious ocular diseases including uveitis, uncontrolled glaucoma, optic atrophy , amblyopia, retinopathies, or inflammatory pathology of the eye;
- history of intraocular trauma, surgery, or retinal laser procedures;
- usage of systemic or topical steroids or NSAIDs within one month prior to surgery;
- patients with diabetes or any other systemic diseases that might confound the results or increase the risk for postoperative inflammation;
- intraoperative complications such as capsule tear, hyphema, vitreous loss, iris manipulation, or miosis after laser pre treatment requiring intracameral injection of epinephrine;
- ocular conditions contraindicating FLACS including poorly dilated pupils (<5.0mm), narrow palpebral fissure, small hyperopic eyes with steep cornea (difficult to achieve suction), severe conjunctival chalasis, nystagmus, or lack of cooperation;
- potentially pregnant women;
- known sensitivity to concomitant medications used during perioperative period, participation in other clinical trial during the time of visit, or poor cooperation in diagnostic tests or non-compliance at follow-up.