Overview

Gallium-68-DOTATOC binds primarily with high affinity to somatostatin subtype 2 (SSTR2) receptors and these somatostatin receptors are also overexpressed on inflammation cells when activated.

The hypothesis is that the GATED mode on a Gallium-68-DOTATOC cardiac recording would be able to highlight abnormalities that could be correlated with the age of the patients and their cardiovascular risk factors.

Eligibility

Inclusion Criteria:

        Persons who have received complete information on the organization of the research and who
        have signed the informed consent and:
          -  Age ≥ 18 years old.
          -  Having read and understood the information document.
          -  Affiliated to a social security scheme.
        Person for whom a 68Ga-DOTATOC PET/CT exam is requested as part of the diagnostic or
        pre-therapeutic assessment of a neuroendocrine tumour.
        Exclusion Criteria:
        Person with
          -  Hypersensitivity during previous use of 68Ga-DOTATOC
          -  Impossibility of performing a PET-CT (patient agitated, confused, etc.).
          -  History of heart disease,
          -  Severe arrhythmia that does not allow the PET synchronized with the ECG
          -  Severe renal insufficiency (GFR <30 ml/min/1.73 m2)
          -  Treated with a somatostatin analogue.
          -  Cushing's syndrome
          -  Pregnant woman, likely to be or breastfeeding
          -  Adult subject to a legal protection measure (guardianship, curators, legal safeguard)
          -  Person of legal age unable to express their consent
          -  Person deprived of liberty by a judicial or administrative decision
          -  Person, subject to psychiatric care under articles L. 3212-1 and L. 3213-1