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Changes in Attentional Control After a Focal Seizure.

Changes in Attentional Control After a Focal Seizure.

Recruiting
18-80 years
All
Phase N/A

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Overview

Epilepsy is frequently associated with cognitive and attentional disorders. Several studies have pointed out that there are modifications of brain activity in resting state during peri-ictal period in EEG and functional MRI. However, to date, no study has assessed the changes in attentional control after a seizure. The investigators hypothesize that a localized discharge is associated with a disorganization of the networks engaged in attentional control. In this regard, the investigators propose a prospective longitudinal study assessing the changes in attentional control after a focal seizure.

Eligibility

Inclusion Criteria:

  • Age superior to 18 and under 80
  • Focal epilepsy with indication to pre-surgery work-up and 5 days programmed hospitalization dedicated to this work-up
  • Normal global cognitive performance (MoCA ≥ 26)
  • Be affiliated to the social security system
  • Have signed an informed consent

Exclusion Criteria:

  • Pregnancy or breastfeeding
  • Not able to give consent (Article 1121-8 of the CSP)
  • Vulnerable person
  • Being deprived of liberty by judicial or administrative decision (Article L 1121-6 of the CSP)
  • Guardianship
  • Have a high probability of not respecting the protocol or of abandoning the study
  • Absence of any epileptic seizure recorded during the hospitalization
  • Recurrent seizures preventing the recording of at least 24 hours without any seizure following a seizure.

Study details
    Temporal Lobe Epilepsy
    Frontal Lobe Epilepsy
    Others Subtypes

NCT06466681

University Hospital, Lille

26 June 2024

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