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VTEval Project - Prospective Cohort Studies to Evaluate and Improve Diagnostics, Management Strategies and Risk Stratification in VTE

VTEval Project - Prospective Cohort Studies to Evaluate and Improve Diagnostics, Management Strategies and Risk Stratification in VTE

Recruiting
18 years and older
All
Phase N/A

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Overview

Venous thromboembolism (VTE) with its two clinical manifestations deep vein thrombosis (DVT) and pulmonary embolism (PE) is a life-threatening disease that is associated with considerable morbidity and mortality. The incidence of VTE increases with age and it - as the third most common cardiovascular disease after ischemic heart disease and stroke - represents an important public health problem in industrialized countries with several aspects in need to be addressed.

VTEval Project includes three long-term prospective observational studies to evaluate and improve VTE diagnostics and management, treatment and outcome. The aims of the project include a systematic assessment of VTE, i.e. disease status (symptoms, clinical and subclinical aspects) and risk profiles (classic, psychosocial and environmental factors), using a system-oriented approach. VTEval collects three large prospective cohorts of patients with suspected and incident VTE consisting of individuals with a clinical suspicion of acute PE, individuals with a clinical suspicion of acute DVT, and individuals with incidental diagnosis of VTE).

The standardized and harmonized data acquisition of the study establishes a sustainable resource for comprehensive research on VTE, thus providing the basis for both short- and long-term analysis.

Eligibility

Inclusion Criteria:

  • Age ≥18 years and Informed written consent
  • Clinical condition:
    • Cohort 1: Clinical suspicion of acute PE (with or without DVT)
    • Cohort 2: Clinical suspicion of acute DVT (without symptomatic PE)
    • Cohort 3: Incidentally diagnosed VTE

Study details
    Venous Thromboembolism (VTE)
    Deep Vein Thrombosis (DVT)
    Pulmonary Embolism (PE)

NCT02156401

Johannes Gutenberg University Mainz

23 June 2024

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