Overview
To this study is recruiting non- emergency patients to whom are planning to make coronary artery bypass intervention. From all patients are going to examine transthoracic echo, collect blood samples and register overnight sleep polygraph in a qualified sleep laboratory two times; first before cabg and second one after surgery.
Description
Detailed Description:
Hypothesis, that sleep related apneas are increasing after coronary artery bypass surgery and sleep quality may deteriorate. We are trying to find out reasons which are leading to these problems which are caused by microemboli in the brain from using heart lung machine, brain infarction caused by major surgery, thorax tissue trauma after operation or complications under perioperative treatment. Hypothesis is that if a patient is diagnosed with sleep apnea before cabg surgery, are postoperative results connected with postoperative outcomes and recovery. Sleep polygraph is made before surgery and approximately six months after surgery and transthoracic echo and laboratory tests. If connection between sleep quality and coronary bypass surgery can be made, findings can be used in clinical practice.
Total amount of heart lung machine treated patients is waited to be 70. Off pump patient sample size is remarkably smaller so data is collected and compared with main sample population. Operation technique is decided when patient is scheduled to operation. Emergency patients are excluded, because pre- operative researches cannot be performed. Coronary artery disease is causing recruiting challenges, because patients often need urgent care. Other exclusion criteria are night time cpap- treatment and other heart operations (for example valvesurgery) during cabg.
From all of the patients are collected basic information including age, weight, heigh, diseases, medication and medical history. Ekg is registered before and after surgery and sinus or other heart rhythms are recorded. Sleep polygraph six months postoperatively, when the patient is fully recovered from surgery.
Eligibility
Inclusion Criteria:
Elective coronary artery bypass surgery
Exclusion Criteria:
- Emergency cabg
- Night time cpap- treatment
- other heart operations (for example valve surgery)