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Molecular Characteristics and Prevalence of Viral Hepatitis E in Human Tissue and Cell Donors

Molecular Characteristics and Prevalence of Viral Hepatitis E in Human Tissue and Cell Donors

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Overview

In this study, the researchers want to focus on the prevalence of anti-HEV antibodies by a new generation test, direct detection of HEV RNA, and its genotypic analysis in a group of human tissue and cell donors.

Description

At the Department of Laboratory Medicine of the Faculty of Medicine of the Faculty of Medicine of the National University of Health Sciences, human tissue and cells from donors will be examined for the assessment of health eligibility and donor selection according to Decree No. 422/2008 Coll. According to the current legislation, the determination of IgG and IgM antibodies against HEV or the HEV RNA method is not part of the standard examination of human tissue and cell donors for the assessment of their health eligibility.

Eligibility

Inclusion Criteria:

  • patients indicated for organ or cell donation

Exclusion Criteria:

  • none

Study details
    Hepatitis E

NCT06457438

University Hospital Ostrava

25 June 2024

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