Image

Tailored Versus Traditional Resistance Exercise

Tailored Versus Traditional Resistance Exercise

Not Recruiting
65-80 years
All
Phase N/A

Powered by AI

Overview

Preserving functional ability is crucial for healthy aging. Unfortunately, age-related decreases in muscle power often lead to declines in functional ability. As power is the product of force and velocity, decreases in power can originate from changes in muscle force, contraction velocity, or both, varying between individuals. The primary method to prevent functional disability is power-based resistance training. Although training interventions are effective for most older adults, they do not induce substantial improvements in a subset of the population. These inconsistent outcomes may arise from neglecting the observed differences in the force-velocity (F-v) profiles between individuals. Therefore, this study provides a novel approach to resistance exercise, in which exercise dose is tailored according to the individual's F-v profile. The effectiveness of the tailored method will be assessed in a randomized control trial, comparing the effects of an individualized and a non-individualized 12-week training intervention on muscle power parameters and functional ability.

Eligibility

Inclusion Criteria:

  • Community-dwelling adults
  • 65-80 years old

Exclusion Criteria:

  • Systematic engagement in resistance exercise during the past year
  • Unstable cardiovascular disease, neuromuscular disease, acute infection or fever
  • Recent surgery
  • Lower-extremity injuries
  • Low levels of functional ability (i.e., SPPB score ≤ 9)
  • Cognitive malfunctioning (i.e., Mini-Mental State Examination < 24)

Study details
    Exercise Training

NCT06449716

Universitaire Ziekenhuizen KU Leuven

30 January 2026

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.