Overview
To evaluate bone healing at 4 months after lateral sinus augmentation with a 4:1 ratio of autologous bone and xenograft or xenograft alone. A radiographic volumetric, histomorphometric, and histologic analysis.
Eligibility
Inclusion Criteria:
- Patients of Tufts School of Dental Medicine (TUSDM)
- Two stage sinus augmentations with <5mm (Zinner, Small 2004) residual bone height in need of augmentation for implant placement
- Full maxillary edentulism or Kennedy class I or III
- 18 to 100 year old
Exclusion Criteria:
- Adults unable to consent (cognitively impaired adults)
- Those who self-report as pregnant or breastfeeding
- Wards of the state
- Non-Viable neonates
- Neonates of uncertain viability
- < 18 years of age
- Refusal to participate
- Prior medical condition causing complications in bone metabolism
- Osteoporosis
- History of/or current chemotherapy
- History of/or current head and neck radiation
- Current heavy smoking > 10 cigarettes/day
- Self-reported pregnancy or lactation
- Previous history of sinus elevation procedure
- Existing sinus pathology or pathology discovered at time of sinus augmentation or implant placement
- Absence of autogenous donor site