Overview

To evaluate bone healing at 4 months after lateral sinus augmentation with a 4:1 ratio of autologous bone and xenograft or xenograft alone. A radiographic volumetric, histomorphometric, and histologic analysis.

Eligibility

Inclusion Criteria:

• Patients of Tufts School of Dental Medicine (TUSDM)
• Two stage sinus augmentations with <5mm (Zinner, Small 2004) residual bone height in need of augmentation for implant placement
• Full maxillary edentulism or Kennedy class I or III
• 18 to 100 year old

Exclusion Criteria:

• Adults unable to consent (cognitively impaired adults)
• Those who self-report as pregnant or breastfeeding
• Wards of the state
• Non-Viable neonates
• Neonates of uncertain viability
• < 18 years of age
• Refusal to participate
• Prior medical condition causing complications in bone metabolism
• Osteoporosis
• History of/or current chemotherapy
• History of/or current head and neck radiation
• Current heavy smoking > 10 cigarettes/day
• Self-reported pregnancy or lactation
• Previous history of sinus elevation procedure
• Existing sinus pathology or pathology discovered at time of sinus augmentation or implant placement
• Absence of autogenous donor site