Overview
The main objective of this study was to evaluate the efficacy and safety of drug retention enema for the prevention of acute radiation rectal injury in the real world.
Description
The study was a prospective, multicenter, real-world study with eligible patient data as of May 1, 2024. The prospective study was a continuous, multicenter study.
Eligibility
Inclusion Criteria:
- There are clear indications for radiotherapy (pelvic radiotherapy or rectal radiotherapy) according to relevant guidelines;
- ECOG score 0-1;
- normal mind, clear consciousness;
- High compliance;
- Able to cooperate with the interviewer
Exclusion Criteria:
- Poor compliance, unwilling to participate or unable to cooperate with the interviewer;
- Patients with other intestinal diseases (such as Crohn's disease, rectal ulcer, anal fissure, anal fistula, hemorrhoids, etc.) and perianal diseases;
- serious heart, brain, liver, kidney disease;
- Long-term immune dysfunction;
- Pregnant or lactating women;
- Patients who terminate treatment for various reasons.