Overview
comparing the clinical efficacy of intra-articular injection of platelet lysate (PL), versus Hyaluronic Acid after arthrocentesis in the management of patients with anterior disc displacement with reduction.
Eligibility
Inclusion Criteria:
- Patients that will be diagnosed with anterior disc displacement with reduction (ADDWR) both clinically and through magnetic resonance imaging scan (MRI).
- Patients who will not respond to a previous conservative therapy.
- Patients with pain in temporomandibular joints.
- Patients with normal or limitation in mouth opening.
- Patients with clicking sound.
Exclusion Criteria:
- Patients with previous invasive TMJ surgical procedures.
- Patients with inflammatory or connective tissue diseases.
- Patients with neurologic disorders.
- Patients with history of bony or fibrous adhesion.
- Patients having gross mechanical restrictions and condylar fractures.
- Patients with psychological problems.
- Patients receiving anti-coagulation treatment, non-steroidal anti-inflammatory drugs within 48 hours pre-operatively, corticosteroid injection at the treatment site within one month or systemic use of corticosteroids within 2 weeks.