Overview
- Weakly crossed-linked hyaluronic acid (HA) can be delivered through multiple injections
into the dermal and subnormal layer to improve skin quality. However, this treatment
comes with multiple bumps for several days.
- Alternatively, HA can be delivered after CO2 laser or thulium laser pretreatment. As microscopic analysis after this treatment is limited, the object of the present study is to investigate the morphological cellular changes after CO2 laser and thulium laser delivered HA into human skin.
Eligibility
Inclusion Criteria:
- healthy male and female patients
Exclusion Criteria:
- pregnancy, breast feeding
- open wounds at the area to be treated