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Efficacy of Insulin Like Growth Factor-1(IGF-1) on Bone Regeneration in Intrabony Defects : A Clinico-radiograph Study

Efficacy of Insulin Like Growth Factor-1(IGF-1) on Bone Regeneration in Intrabony Defects : A Clinico-radiograph Study

Recruiting
18 years and older
All
Phase N/A

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Overview

The aim of this study is to clinically evaluate the efficacy of Insulin like Growth Factor (IGF-1) on bone regeneration in intrabony defects.

Description

In test group, after reflection of flap and degranulation, IGF-1 gel with hydroxyapatite will be placed in the defect and sutures will be placed.

In control group, after reflection of flap and degranulation, hydroxyapatite will be placed in the defect and sutures will be placed.

Eligibility

Inclusion Criteria:

        Systemically healthy male and female patients of age >18 years Intrabony defects - two wall
        or three wall defects Probing pocket depths (PPD) of >5mm.
        Exclusion Criteria:
        Medically compromised patients Pregnant women Heavy smokers Patients who underwent
        radiotherapy or chemotherapy are excluded

Study details
    Intrabony Periodontal Defect

NCT06426524

Dr R Viswa Chandra

14 October 2025

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