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An Integrative Multi-Omic Characterization of Head and Neck Carcinogenesis, Progression and Recurrence

An Integrative Multi-Omic Characterization of Head and Neck Carcinogenesis, Progression and Recurrence

Recruiting
18 years and older
All
Phase N/A
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Overview

This study evaluates the cell and biomarkers associated with the aggressive behavior of cancer.

Description

PRIMARY OBJECTIVE:

I. High-resolution single-cell profiling of Cancer-associated fibroblasts (CAFs) in Human papillomavirus (HPV)+ Oropharyngeal Squamous Cell Carcinoma (OPSCC) and metastatic lymph nodes.

OUTLINE: This is an observational study.

Patients undergo photography, blood sample collection, tissue collection and have their medical records reviewed on study.

Eligibility

Inclusion Criteria:

  • Diagnosis/disease status: New diagnosis of head and neck cancer
  • Allowable type and amount of prior therapy: No prior treatment
  • Age ≥ 18 years.
  • Ability to understand and the willingness to sign a written informed consent.

Exclusion Criteria:

  • Patients who have had treatment of head and neck cancer

Study details
    Head and Neck Carcinoma

NCT06420219

University of Southern California

25 May 2024

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