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Early Life Intervention in Pediatrics Supported by E-health - SMOKE

Early Life Intervention in Pediatrics Supported by E-health - SMOKE

Recruiting
5 years and younger
All
Phase N/A

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Overview

Unrestricted parental smoking habits are lifestyle risk behaviors associated with chronic, systemic inflammation, which promotes the pathogenesis of non-communicable diseases (NCDs). Exposure to secondhand tobacco smoke in early life contributes to the development of specific NCDs in children, i.e. asthma. Early preventive measures to improve lifestyle behavior in parents are therefore of utmost importance. The aim of ELIPSE-II is to assess whether an eHealth application intervention for parents is feasible and efficacious in lowering levels of urinary cotinine as a measure of second-hand smoke exposure in their children .

Description

ELIPSE-II represents a single-blind randomized controlled parallel-group clinical trial. In total, 160 children, <6 years of age with exposure to second-hand smoke at home will be included. Children will be recruited at the children's university hospital and in private practices in Bern, and randomly (1:1) assigned to a control and intervention group.

All participants receive treatment-as-usual (TAU), parents of participants in the intervention group additionally receive a smartphone application (lifestyle app) for 20 weeks. The app aims to promote healthy behavior through cognitive-behavioral impact factors (i.e., psychoeducation, goal setting), that are applied by a psychologist via structured feedback. Single-blinded assessments will be conducted at baseline, following the intervention period of 20 weeks, and at 6-month follow-up after the end of the intervention. The primary endpoint is reduction of exposure to second-hand smoke exposure assessed by urinary levels of cotinine. Secondary endpoints in ELIPSE-II include changes in parental smoking habits and effects of the intervention on infants' respiratory health. A further endpoint is acceptance and usability of the app.

Eligibility

Inclusion Criteria:

  • Age: younger than 6 years
  • Exposed to second-hand smoke at home (at least one parent smoking)
  • German speaking parent
  • All sex and ethnic backgrounds
  • Signed informed consent form from parent
  • Children live/grow-up in the same household as the parental participant
  • Referred by a health care professional (e.g. physician, midwife, nurse, other professions)

Exclusion Criteria:

  • Participation in another study/trial targeting similar outcomes
  • Participation in an active smoking cessation programme

Study details
    Smoking Reduction
    Asthma in Children
    Wheezing
    Non-Communicable Disease
    Life Style
    Behavior
    Smoking

NCT06311162

Insel Gruppe AG, University Hospital Bern

25 May 2024

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