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Stellate Ganglion Block for Prevention of Post Mastectomy Depression

Stellate Ganglion Block for Prevention of Post Mastectomy Depression

Recruiting
21-65 years
Female
Phase N/A

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Overview

Complications after mastectomy include chronic pain and depression.

Description

A mastectomy is surgery could be associated with complications include chronic pain and depression. In female breast cancer patients, the incidence of postoperative depression was 46.55%. Stellate ganglion block had been used for treating post-traumatic stress disorder (PTSD) and depression symptoms even in its prevention. Also, it used in treatment of chronic pain.

Eligibility

Inclusion Criteria:

  • Female patients
  • Age ranging from 18 to 65 years
  • American Society of Anesthesiologists (ASA) no more than II
  • Had unilateral cancer breast
  • Scheduled to do unilateral modified radical mastectomy

Exclusion Criteria:

  • Pregnant female
  • Existing Horner syndrome
  • Had any neuromuscular disease
  • Had allergy to local anesthetics
  • History of use of analgesics
  • Had any deformity or a previous surgery in the neck or ipsilateral arm or breast
  • Had any contraindication to the procedure (coagulation disorders, local infection, sepsis)
  • Had any contraindication to the sympathetic blockade (decompensate cardiopulmonary or hemodynamic disorders)
  • History of psychotic disorder including depression, bipolar disorder or personality disorder
  • Patient with Beck Depression Inventory (BDI) score more than 13

Study details
    Mastectomy
    Pain
    Acute
    Pain
    Chronic

NCT06263907

Mansoura University

18 May 2024

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