Overview
The present study will aim to evaluate:
- The presence of Hypoxia Inducible Factor in vitiligo patient
- Defect of Autophagy Related Genes in vitiligo patient
- The cross relation between Autophagy Related Genes and Hypoxia Inducible Factor in the pathogenesis of vitiligo among Egyptian patients in Sohag Governorate
Eligibility
Inclusion Criteria:
- Adult >18 years
- With non segmental vitiligo
- A group of participants will be included as a control group
Exclusion Criteria:
- Pregnancy
- Patient with chronic inflammatory skin disorders
- patient on anti-oxidant or anti-inflammatory drugs
- patient on topical or systemic treatment for vitiligo in last 4 weeks
- patients with other autoimmune diseases
- patients with diabetes mellitus