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Effect of Degenerative Spondylolisthesis on the Clinical Outcome of Unilateral Biportal Endoscopy for Lumbar Spinal Stenosis: Study Protocol

Recruiting
50 - 80 years of age
Both
Phase N/A

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Overview

A single-center, prospective cohort trial aims to provide stronger evidence regarding the impact of degenerative spondylolisthesis on the clinical outcome of unilateral biportal endoscopy for lumbar spinal stenosis

Eligibility

Inclusion Criteria:

  • Age range: 50-80 years
  • Diagnosis of LSS affecting 1-2 vertebral levels
  • Predominant manifestation of neurogenic intermittent claudication, with ineffective conservative treatment for at least 3 months
  • Presence of lumbar DS of less than grade II or absence of spine instability
  • Willingness to participate in the study and complete follow-up assessments.

Exclusion Criteria:

  • Diagnosis of isthmic lumbar spondylolisthesis or lumbar DS of grade ≥II
  • Evidence of instability at the affected vertebral level (intervertebral angle change exceeding 15° in standing flexion-extension radiographs of the lumbar spine)
  • History of prior surgery at the affected vertebral level
  • Presence of scoliosis with a Cobb angle > 20º
  • Presence of other conditions affecting the lumbar spine (infection, tumor, fracture, neurological diseases, and others)
  • Medical disorders that preclude surgical tolerance
  • Participation in other clinical research projects related to the treatment of lumbar spinal stenosis.

Study details

Degenerative Spondylolisthesis, Lumbar Spinal Stenosis

NCT06394089

Beijing Friendship Hospital

25 May 2024

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