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Ultrasound Evaluations of Diaphragm and Intercostal Muscle to Predict the Failure of High-Flow Nasal Cannula Therapy

Ultrasound Evaluations of Diaphragm and Intercostal Muscle to Predict the Failure of High-Flow Nasal Cannula Therapy

Recruiting
18 years and older
All
Phase N/A

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Overview

The study aims to predict the failure of High-flow Nasal Cannula oxygenation therapy by ultrasound evaluation of diaphragm and intercostal muscle contraction during the first 24 hours.

Eligibility

Inclusion Criteria:

  • more than 18 years old
  • needing High-flow Nasal Cannula oxygenation therapy

Exclusion Criteria:

  • received mechanical ventilation, including invasive or noninvasive ventilation within one month prior to enrollment
  • history of neuromuscular disorders (e.g., myasthenia gravis, Guillain-Barre syndrome);
  • immediate endotracheal intubation is required (life-threatening hypoxemia)
  • extensive damage to the thoracic skin (e.g., burns) unable to undergo ultrasonography
  • pregnancy
  • attending physician deemed it inappropriate to participate in the trial.

Study details
    High-flow Nasal Cannula
    Ultrasound Evaluation
    Diaphragm and Intercostal Muscle

NCT06375538

Shanghai Zhongshan Hospital

3 May 2024

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