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Real-World Clinical Experience of Patients With Metastatic Castration-Resistant Prostate Cancer Treated With Olaparib + Abiraterone (PROceed)

Real-World Clinical Experience of Patients With Metastatic Castration-Resistant Prostate Cancer Treated With Olaparib + Abiraterone (PROceed)

Recruiting
Male
Phase N/A

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Overview

PROceed is a multisite, prospective, observational study that describes the real-world use and clinical experience of mCRPC patients treated with the combination of olaparib and abiraterone in the mCRPC setting. Clinical outcomes will be assessed in patients who are either NHA-naive or NHA-exposed prior to initiating olaparib + abiraterone treatment, respectively. Patient demographic and clinical characteristics, as well as treatment received prior and subsequent to olaparib + abiraterone, will also be described. The study plans to enroll patients for a maximum of 2 years and follow up patients from initiation of olaparib until 1 year post last patient in.

Eligibility

Inclusion Criteria:

  • Willing and able to provide written informed consent;
  • 18 years of age and above;
  • Documented histopathology or cytopathology of PCa, adenocarcinoma;
  • Confirmed as mCRPC;
  • Initiated olaparib + abiraterone after site activation

Exclusion Criteria:

  • Patients participating in a clinical trial with an investigational prostate cancer treatment within 30 days prior to olaparib initiation

Study details
    Metastatic Castration-resistant Prostate Cancer

NCT06380738

AstraZeneca

29 May 2024

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