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Molecular Mechanisms of Fibrillin/LTBP Superfamily in Renal Fibrosis and Cardiorenal Syndrome

Molecular Mechanisms of Fibrillin/LTBP Superfamily in Renal Fibrosis and Cardiorenal Syndrome

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20 years and older
All
Phase N/A
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Overview

This project is to understand the LTBP4 expression in human renal fibrotic tissues. The investigators will exam major location of LTBP4 expression and check any similar or discrepancy in renal fibrosis with different etiologies.

Description

The investigators will obtain the residual renal tissues with different etiologies and check the expression of LTBP4. The location and quantitation of LTBP4 in renal tissues will be checked. It will be great to understand the association between the severity of fibrosis and the expression of LTBP4 and other matrix proteins.

Eligibility

Inclusion Criteria:

  • Abnormal kidney function, proteinuria, hematuria

Exclusion Criteria:

  • N/A

Study details
    Renal Fibrosis
    CKD

NCT05012228

National Taiwan University Hospital

2 May 2024

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