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Impact of Non-surgical Periodontal Treatment of miRNome

Impact of Non-surgical Periodontal Treatment of miRNome

Recruiting
18-70 years
All
Phase N/A
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Overview

A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment by means of minimally invasive approach MINST or Q-SI (quadrantwise) approach in subjects with periodontitis on miRNome in gingival crevicular fluid

Description

A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment in subjects with periodontitis.

60 patients: 30 with periodontitis and 30 healthy controls. All the patients are assessed for clinical, periodontal, blood following of minimally invasive approach MINST or Q-SI (quadrantwise).

Measurements are taken before and after initial periodontal treatment in the periodontal subjects.

Eligibility

Inclusion Criteria:

  • Diagnosis of Periodontitis

Exclusion Criteria:

  • Periodontal treatment
  • Use of antibiotics, NSAIDs, and immunosuppressants during the last 6 months
  • Pregnancy

Study details
    Periodontitis

NCT06382935

University of Catania

2 May 2024

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