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PD-L1 Specific [68Ga]-Nb-1 Nanobody Probe for PET Imaging in Solid Tumors

Recruiting
18 - 70 years of age
Both
Phase N/A

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Overview

The objective of the study is to constrcut a noninvasive approach 68Ga-Nb-1 PET/CT to detect the PD-L1 expression of tumor lesions in patients with solid tumors and to identify patients benefiting from anti-PD-L1 treatment.

Eligibility

Inclusion Criteria:

  1. Aged >18 years old; ECOG 0 or 1;
  2. Patients with solid tumors;
  3. Has at least one measurable target lesion according to Response Evaluation Criteria in Solid Tumors (RECIST V1.1);
  4. life expectancy >=12 weeks.

Exclusion Criteria:

  1. Significant hepatic or renal dysfunction;
  2. Is pregnant or ready to pregnant;
  3. Cannot keep their states for half an hour;
  4. Refusal to join the clinical study;
  5. Suffering from claustrophobia or other mental diseases;
  6. Any other situation that researchers think it is not suitable to participate in the experiment

Study details

Solid Tumor

NCT06383598

Peking University Cancer Hospital & Institute

1 May 2024

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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