Overview
In our prior research, a risk scoring model for the occurrence of lymph node metastasis in patients who underwent radical gastrectomy for gastric cancer was established. To further validate this scoring model, a prospective study has been designed with the aim of prospectively assessing the model's clinical applicability.
Description
The study was a single-centre, prospective study. Data prospectively accrued were employed to evaluate the concordance between observed patient outcomes, with respect to lymph node metastasis status post-curative gastrectomy, and the prognostications tendered by the established risk scoring model, thereby appraising the model's clinical applicability and validity.
Eligibility
Inclusion Criteria:
- Primary gastric adenocarcinoma;
- Curative surgery (with R0 resection, excluding palliative surgery and cases with distant metastasis).
Exclusion Criteria:
- Patients with autoimmune diseases, inflammation, or hematological disorders;
- Patients with a history of or concurrent other cancers;
- Presence of active infection and inflammation (based on WBC count, patients with count of 10×10^9 or higher should be evaluated through medical record examination for the presence of infection);
- Active bleeding (as determined by endoscopic ultrasound and HGB ≤ 90);
- Post neoadjuvant radiotherapy or chemotherapy;
- History of blood transfusion, corticosteroid use, or leukocyte-stimulating medications within the past month prior to blood draw;
- Incomplete clinical and pathological data.