Overview
The aim of this study is to identify genetic factors that contribute to risk and progression of early-onset dementia (loss of memory function before the age of 70 years) across all ethnic groups, including Alzheimer's Disease, mild cognitive impairment and other dementias.
Description
The study population includes individuals affected by Alzheimer's Disease, mild cognitive impairment, other dementias, cognitively healthy individuals without memory problems, or their family members.
Ascertainment is across both males and females, and all race and ethnic groups.
Eligibility
Inclusion criteria:
- 18 years and older
- Individuals diagnosed with dementia, their family members and unrelated healthy controls without dementia.
Exclusion Criteria:
-Individuals with competing diagnosis such as Huntington's disease, traumatic brain injury, drug or alcohol abuse, or schizophrenia, etc., unless family members of a dementia affected individual