Overview
The aim of this clinical trial is to evaluate the effect of using intra-radicular cryotherapy technique in the form of irrigation with cold sodium hypochlorite
The main questions to answer are:
- Does Postoperative pain is different between the three groups?
- Does level of substance P different between the three groups ?
Description
- The patients will be randomly divided into three groups Group 1: control group (n=25)
Regular root canal treatment with regular irrigant will be used. Group 2: (n=25)
Intraradicular cryotherapy will be performed where :
- Normal root canal treatment will be done with irrigation using sodium hypochlorite cooled to 2°C continuously during our mechanical instrumentation. Then a final flush will be done with cold saline 2°C for 5 minutes. Group 3: (n=25) Normal root canal treatment will be done with irrigation using sodium hypochlorite at room temperature during our mechanical instrumentation. Then a final flush will be done with cold saline 2°C for 5 minutes.
Eligibility
Inclusion Criteria:
- Patients that will be diagnosed with symptomatic apical periodontitis
- Single-rooted premolars (radiographically and clinically assessed)
- Medically free patients.
- Teeth with mature apex
Exclusion Criteria:
- Patients with other pulpal diagnosis.
- Medically compromised patients.
- Pregnant females.
- Patients taking analgesics or anti-inflammatory drugs.