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Effect of the Association of Berberine Fitosoma® and Monacolin K MonaKoPure® on Glyco-metabolic Parameters in Dysglycemic and Dyslipidemic Patients.

Recruiting
18 - 70 years of age
Both
Phase N/A

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Overview

The objective of this study is to evaluate the effectiveness of the association Berberina Fitosoma® and monacolin K MonaKoPure® (Berberol® K supplement) compared to placebo on glucidic and lipid parameters in subjects with fasting blood glucose (FPG) values between 100 and 125 mg/dl and with total cholesterol (TC) values ≥ 200 mg/dl.

Description

The objective of this study is to evaluate the effectiveness of the association Berberina Fitosoma® and monacolin K MonaKoPure® (Berberol® K supplement) compared to placebo on glucidic and lipid parameters in subjects with fasting blood glucose (FPG) values between 100 and 125 mg/dl and with total cholesterol (TC) values ≥ 200 mg/dl.

Eligibility

Inclusion Criteria:

  • Overweight or obese subjects [according to body mass index (BMI)]
  • Fasting plasma glucose value between 100 and 125 mg/dl, with impaired fasting glucose or impaired glucose tolerance confirmed with oral glucose tolerance test (OGTT)
  • Total cholesterol values ≥ 200 mg/dl

Exclusion Criteria:

  • Patients with neoplastic and liver diseases, renal failure
  • Patients with type 1 or 2 diabetes mellitus
  • Pregnant or breastfeeding women
  • Hypersensitivity to any of the ingredients
  • Therapy with lipid-lowering drugs
  • Use of products containing red yeast rice

Study details

Dyslipidemias, Dysglycemia

NCT06348550

University of Pavia

15 April 2024

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