Overview
This study is being done to determine the effectiveness of using a combination of two different drugs in preventing the transmission of HCV from a HCV positive donor to a HCV negative solid organ recipient.
Eligibility
Inclusion criteria:
- Listed kidney, heart, lung and/or pancreas patients who are negative for chronic hepatitis C infection
- Willing to accept and consent for accepting hepatitis C positive graft
Exclusion criteria:
- Existing chronic liver disease (liver cirrhosis)
- Concomitant infection with HIV or Chronic hepatitis B
- Patient or any member of patient family or care giver team who does not understand or accept the risk of an acquired HCV infection
- Pregnancy (Pregnant patients do not undergo solid organ transplants)