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Assessment of Periprosthetic Bone Mineral Density in Patients Undergoing Total Knee Prosthesis of Different Design

Assessment of Periprosthetic Bone Mineral Density in Patients Undergoing Total Knee Prosthesis of Different Design

Recruiting
45 years and older
All
Phase N/A

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Overview

compare changes in BMD via DXA at the level of the femoral and tibial periprosthetic bone between two groups of patients undergoing cemented TKA of different design (posterior stabilization vs posterior cruciate preservation) with proms at a 2-year follow-up.

Eligibility

Inclusion Criteria:

  1. Patients aged ≥ 45 years
  2. Patients who are candidates for primary cemented total knee replacement based on physical examination and medical history, including diagnosis of severe knee pain and disability due to at least one of the following:
        to. Primary or secondary osteoarthritis b. Collagen disorders and/or avascular necrosis of
        the femoral condyle c. Moderate valgus, varus or flexion deformities (HKA within ±10°,
        flexion contracture <10°) 3. Patients consenting and able to complete planned study
        procedures and follow-up assessments 4. Patients informed about the nature of the study who
        signed the "informed consent" approved by the ethics committee.
        Exclusion Criteria:
          1. Patients aged < 45 years;
          2. Patients who have already undergone hip or knee arthroplasty ankle, previous
             osteotomy, with severe axial deformities or suffering from rheumatoid arthritis,
             diabetes or neuromuscular diseases. In this way, homogeneity of the investigated
             cohort will be guaranteed;
          3. Pregnant women. -

Study details
    Periprosthetic Osteolysis

NCT06309433

Istituto Ortopedico Rizzoli

21 March 2024

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