Image

A Study of Opportunistic Salpingectomy to Prevent Ovarian Cancer

A Study of Opportunistic Salpingectomy to Prevent Ovarian Cancer

Recruiting
45 years and older
Female
Phase N/A

Powered by AI

Overview

The purpose of this study is to find out how many participants are interested in a surgical preventive procedure after watching an educational video. Before and after watching the video, participants will complete questionnaires in the clinic.

Eligibility

Inclusion Criteria:

Part I

  • Age ≥45 years
  • Scheduled visit with a nongynecologic surgeon
  • Female or assigned female at birth

Part II

  • Age ≥45 years
  • At least one in situ fallopian tube
  • No desire or plan to have children in the future
  • Average risk of developing ovarian cancer

    ° Note: Average risk patients are defined as patients with no known genetic risk factor for developing ovarian cancer. Patients who, after obtaining family history, are suspected to have a hereditary ovarian cancer syndrome but have not yet been tested, will be referred for genetic evaluation.

  • Planned nongynecologic, intraabdominal, or pelvic surgery
  • Deemed to be a suitable candidate by gynecologic surgeon and primary nongynecologic surgeon (for example, on the basis of surgical history and current malignancy status)
  • Approved and signed informed consent

Exclusion Criteria:

Part I

  • Not fluent in English

    ° If there is a non-english speaking participant who is a strong candidate and meets all other criteria for Part 2, they are able to go directly onto Part 2 without completing Part 1. (Please see additional details in section 4.1 and 7.0.)

  • Known inherited ovarian cancer susceptibility

Part II

  • Personal history of a gynecologic malignancy
  • Carrier of a hereditary breast or ovarian cancer variant (e.g., BRCA1, BRCA2, BRIP1, PALB2, RAD51C, RAD51D, MLH1, MSH2, MSH6, PMS2)
  • Suspicious ovarian, fallopian tube, or uterine lesion on preoperative imaging
  • Previous bilateral salpingectomy or bilateral salpingo-oophorectomy
  • Current pregnancy
  • Emergent procedure or emergency procedure that has to be completed within 24 hours where clinical consent occurs in the inpatient setting or where the patient's immediate well-being is in danger or condition may be life threatening
  • Primary surgeon anticipates that OS will add significant time (>30-40min) to the planned procedure.
  • Inability to access the pelvis (ex., patient prone/lateral position) during the planned procedure.
  • Known history of pelvic fibrosis or significant adhesions.
  • Procedures with palliative intent only

Study details
    Surgery

NCT06312124

Memorial Sloan Kettering Cancer Center

24 June 2024

Step 1 Get in touch with the nearest study center
We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team

Investigator Avatar

Primary Contact

  Other languages supported:

First name*
Last name*
Email*
Phone number*
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.