Overview
The goal of observational study is to Evaluation of the effectiveness of the self-developed pulmonary lobar ventilation detector in Chronic Obstructive Pulmonary Disease. The main question it aims to answer are:Evaluation of the effectiveness of the self-developed pulmonary lobar ventilation detector.
Participants will use the self-developed pulmonary lobar ventilation detector and the imported Chartis detection system to evaluate the target pulmonary lobar collateral ventilation.
Eligibility
Inclusion Criteria:
- Patients with chronic obstructive pulmonary disease who meet the GOLD diagnostic criteria
- FEV1 ≤ 45% pred and FEV1/FVC<70%
- TLC>100% pred and RV>175% pred
- CAT≥18
- >50% of emphysema destruction
- Smoking prohibition>6 months
- Sign the informed consent form
Exclusion Criteria:
- PaCO2>8.0 kPa, or PaO2<6.0 kPa
- 6-minute walking test<160m
- Obvious chronic bronchitis, bronchiectasis or other infectious lung diseases
- Three hospitalizations due to pulmonary infection in the past 12 months before the baseline assessment
- Previous lobectomy, LVRS or lung transplantation
- LVEF<45% and or RVSP>50mmHg
- Anticoagulant therapy that cannot be stopped before surgery
- The patient has obvious immune deficiency
- Participated in other lung drug studies within 30 days before this study
- Pulmonary nodules requiring intervention
- Any disease or condition that interferes with the completion of the initial or subsequent assessment