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Filling Key Research Gaps With Clinical Implications in Mansonellosis and Schistosomiasis: a Network Approach

Filling Key Research Gaps With Clinical Implications in Mansonellosis and Schistosomiasis: a Network Approach

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Overview

This is an experimental, multicenter, non-profit study promoted by the Department of Infectious and Tropical Diseases of the IRCCS (Istituto di Ricerca e Cura a carattere scientifico) Sacro Cuore Don Calabria of Negrar which aims to evaluate the presence of endosymbiont Wolbachia in circulating microfilariae obtained from biological samples of individuals infected with M .perstans and the presence of infection with hybrid Schistosoma species in the population of Schistosoma eggs isolated from biological samples of patients with active schistosomiasis.

Eligibility

Inclusion criteria:

  • samples from patients who gave consent to the storage and use for research purposes of their samples. In the case a network centre necessitates a template for the storage and use for research purposes of their samples;
  • samples collected before any treatment with praziquantel and/or benzimidazole and/or avermectin and/or diethylcarbamazine and/or doxycycline drug;
  • samples collected and stored in conditions suitable for this study (Annex 2);
  • known country of birth of the patient or of most likely infection (if different from the country of birth)

Exclusion criteria:

  • no compliance with at least one of the above-mentioned inclusion criteria.

Study details
    Schistosoma Mansoni

NCT06311344

IRCCS Sacro Cuore Don Calabria di Negrar

21 March 2024

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