Overview
Exploring the ED90 of remimazolam in pediatric bidirectional endoscopy at different age groups.
Description
Exploring the ED90 of remimazolam in pediatric bidirectional endoscopy at different age groups, providing a more scientific clinical dose selection basis for the anesthesia induction application of Remazolam.
Eligibility
Inclusion Criteria:
- Age 0-12 years old,
- ASA I-II level;
- Sign an informed consent form.
Exclusion Criteria:
- Developmental delay or neurological and psychiatric disorders;
- Severe malnutrition or severe obesity;
- High risk of stomach fullness and reflux aspiration;
- Allergic to benzodiazepines and opioids;
- Those who have taken sedative, analgesic, or antidepressant drugs within 24 hours;
- Severe sleep apnea;
- Abnormal liver and kidney function;
- Recently participated in other clinical studies.