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Esophageal Cancer Multimodal Prehabilitation Study

Esophageal Cancer Multimodal Prehabilitation Study

Recruiting
65 years and older
All
Phase N/A

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Overview

The goal of this research study is to investigate the feasibility of implementing a prehabilitation program that aims to improve a patient's physical, nutritional, and sleep health before surgery in an older, at-risk group with esophageal cancer.

Description

This research study is to test whether a novel, 4-week surgical multimodal prehabilitation protocol is feasible in at-risk older adult patients who have previously undergone neoadjuvant chemotherapy or radiotherapy and are scheduled for surgical removal of esophageal cancer.

Research study procedures include screening for eligibility, clinic visits, questionnaires, blood tests, and Computed Tomography (CT) scans.

Participation in this research study is expected to last 7 months.

It is expected about 30 patients will participate in this study.

Eligibility

Inclusion Criteria:

  • 65 years of age and over
  • Adult male or non-pregnant female volunteers
  • Completed neoadjuvant chemotherapy or radiotherapy for esophageal cancer
  • At least four weeks to esophageal cancer surgery
  • Without skin conditions that preclude wearing sensors
  • Able to speak English and consent

Exclusion Criteria:

  • Participants in any other interventional study that may bias results or limit study adherence during our study
  • Dietary restrictions that prevent consumption of nutritional supplements
  • Women who are pregnant, nursing, or at risk of becoming pregnant
  • Profound physical disability (for example, quadriplegia) that precludes participation in any aerobic or strength training.

Study details
    Esophageal Cancer
    Esophageal Neoplasms

NCT06027515

Massachusetts General Hospital

19 May 2025

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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