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Pain AND Opioids After Surgery

Pain AND Opioids After Surgery

Recruiting
18 years and older
All
Phase N/A

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Overview

The aim of this study is to document the perioperative opioid use and its safety in the UK and countries in Europe and to describe its association with surgical complications, persistent pain and quality of life. In an international, prospective, observational cohort study, data about the perioperative pain management will be collected in all eligible hospitalised adult patients who undergo surgery in a designated "study week" in as many hospitals as possible in Europe. Baseline data will be collected, and participants followed up at one week, and at three and twelve months post-operatively. The primary outcome will be opioid use at three months after surgery. Secondary outcomes will include opioid use during the preoperative month (preoperative use), during surgery and up to one week after surgery (or discharge, whichever is earlier), and up to the end of the postoperative year. Additional secondary outcomes are the incidence of preoperative pain, persistent pain with/without the presence of neuropathic components, quality of life and surgical complications. The potential association between opioid use and pain outcomes will be investigated. This study could help to develop strategies to improve quality of care, through pain management, for patients undergoing surgery.

Eligibility

Inclusion Criteria:

  • hospitalised adult patients (18 years and older) undergoing any inpatient surgery (elective or emergency) during the designated study week where an anaesthetist is involved (general anaesthetic, sedation, local anaesthetic).

Able to understand and has capacity to give written informed consent

Exclusion Criteria:

  • American Society of Anaesthesiologists (ASA) grade V or VI
  • Refusal to participate.
  • Lack of comprehension of validated questionnaires or inability to complete the follow-up for any reason.
  • Lack of capacity to give written informed consent

Study details
    Opioid Use
    Pain
    Chronic
    Pain
    Postoperative
    Quality of Life

NCT05877157

University of Aberdeen

8 March 2024

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