Overview
A randomized controlled trial comparing the vaginal, vNOTES ( vaginal natural orifice transluminal surgery) or laparoscopic approach for hysterectomy in women with benign gynaecological disease
Description
Multi-center pragmatic non-blinded RCT including 1000 women 18-75 years in need of hysterectomy for benign disease; comparing VH vs vNOTES or LH vs vNOTES.
Eligibility
Inclusion Criteria:
• Women aged 18 to 75 years regardless of parity with benign indication for hysterectomy
Exclusion Criteria:
- Women with a stage II+ prolapse in need of a hysterectomy as part of vaginal prolapse repair
- hysterectomy due to suspected endometriosis
- subtotal hysterectomy
- history of rectal surgery
- suspected malignancy
- suspected obliteration of the pouch of Douglas following severe PID or other causes
- active lower genital tract infection
- pregnancy
- failure to provide written informed consent prior to surgery
- requirement of in-patient care due to other co-morbidities