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Gravitas Feeding Tube System Placement Validation in Neonates

Recruiting
- 18 years of age
Both
Phase N/A

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Overview

The purpose of this study is to validate the Gravitas Feeding Tube System Placement Algorithm for NICU patients and to evaluate the safety and effectiveness of the Gravitas Feeding Tube in the neonate population for the administration of nutrition, fluids and medications.

Eligibility

Inclusion Criteria:

  • Infants in the Newborn Intensive Care Unit or on the general medical floor requiring a 5-8 Fr NG tube. The desired size of the feeding tube should be determined clinically, and the Gravitas 5-8 Fr Feeding Tube should only be placed if that size is appropriate.
  • Age at enrollment: 0 to 18 weeks post-partum. Can be up to 12 weeks preterm (gestational age ≥ 28 weeks).
  • Suitable to start enteral (gastric but not post-pyloric) feeding
  • Anticipated to receive enteral feeding (either bolus or continuous feeds) for more than 6 hours. If enteral nutrition has already been initiated, indicated for replacement of an orogastric/nasogastric feeding tube.
  • Ability to have a legally authorized representative provide informed consent Both neonates on a ventilator (non-invasive or invasive ventilation) or not requiring a ventilator are eligible for this study.

Exclusion Criteria:

  • Known major upper airway malformation (e.g. tracheoesophageal fistula)
  • Known major GI malformation (e.g. malrotation)
  • NPO status - neonate expected to remain NPO/NPG for the following 72 hours
  • Has a medical condition that drastically affects gastric acid-secretion (e.g. Zollinger-Ellison Syndrome, congenital achlorhydria, gastrointestinal perforation/leak/obstruction);
  • Has had removal of part of the stomach
  • Critically ill, facing imminent death
  • Neonate on ECMO
  • Deemed unsuitable for enrollment in study by the site principal investigator based on the patients' medical history
  • Infant needs an MRI in the immediate future (e.g. 6-12h)
  • Infant needs post-pyloric feeds (distal to stomach)
  • Infant has a basilar skull fracture

Study details

Nasogastric Tube

NCT05914064

Gravitas Medical, Inc.

8 March 2024

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