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The Effect of Rehabilitation Training on Orthostatic Hypotension in Parkinson's Patients

Recruiting
40 years of age
Both
Phase N/A

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Overview

The goal of this clinical trial is to explore raise-bed training Orthostatic Hypotension in Parkinson's Patients. The main question it aims to answer is:

Can raise-bed training improve Orthostatic Hypotension in Parkinson's Patients. Patients will be randomly allocated into the control group or the experimental group, all under rehabilitation treatment, the experimental group will be given raise-bed training. The study lasts 21 days for each patient. Researchers will compare Orthostatic Hypotension Questionnaire, Orthostatic Grading Scale, Composite Autonomic Symptom Scale 31 to see if raise-bed training can help improve the symptom.

Description

Orthostatic Hypotension is common in Parkinson's Patients. The goal of this clinical trial is to explore raise-bed training Orthostatic Hypotension in Parkinson's Patients. The main question it aims to answer is:

Can raise-bed training improve Orthostatic Hypotension in Parkinson's Patients. Patients will be randomly allocated into the control group or the experimental group, all under rehabilitation treatment, the experimental group will be given raise-bed training. The study lasts 21 days for each patient. Researchers will compare Orthostatic Hypotension Questionnaire, Orthostatic Grading Scale, Composite Autonomic Symptom Scale 31 to see if raise-bed training can help improve the symptom.

Eligibility

Inclusion Criteria:

  • Confirmed diagnosis of Parkinson's disease
  • Presence of orthostatic hypotension, defined as a decrease in systolic blood pressure of at least 20 mmHg or a decrease in diastolic blood pressure of at least 10 mmHg within three minutes of standing up
  • Age 40 years or older
  • Willingness to participate in the study and provide informed consent

Exclusion Criteria:

  • Severe cardiovascular disease or other medical conditions that would make head-up tilt treatment unsafe or inappropriate
  • Use of medications that affect blood pressure or heart rate, such as beta-blockers or vasodilators, and inability or unwillingness to discontinue these medications for the study period
  • History of syncope or falls within the past six months
  • Inability to stand or sit up independently or tolerate changes in body position
  • Cognitive impairment or inability to provide informed consent

Study details

Orthostatic Hypotension

NCT06255717

Zeng Changhao

8 March 2024

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