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Magnesium and Riboflavin Treatment for Post-Concussion Headache

Magnesium and Riboflavin Treatment for Post-Concussion Headache

Recruiting
18-40 years
All
Phase 2

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Overview

This clinical trial will try to determine if the supplements magnesium and riboflavin will reduce the pain and duration of headaches in persons diagnosed with a concussion. The participant will be randomized to either active magnesium and riboflavin capsules or placebo (inert) capsules. The capsules will be taken once a day for 14 days. The participant will also complete a short diary form for the 14 days and will have 3 follow up visits either by telephone or in person.

Eligibility

Inclusion Criteria:

  • Seen at University of Virginia Student Health and Wellness Center or Emergency Department for Initial Visit for Concussion;
  • Less than 3 days have elapsed since their injury;
  • Able to swallow capsules

Exclusion Criteria:

  • Concussion complicated by cranial bleed, skull fracture, additional severe injury;
  • Kidney disfunction or failure;
  • Significant gastro-intestinal dysfunction;
  • Varsity Athlete;
  • Two or more previous concussions;
  • Women who are pregnant or breast feeding;
  • Taking tetracycline, fluoroquinolone, iron digoxin, chlorpromazine or penicillamine

Study details
    Concussion
    Intermediate

NCT06260072

University of Virginia

22 February 2024

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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