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Multi-Component Prehabilitation for Major Elective Surgery

Multi-Component Prehabilitation for Major Elective Surgery

Not Recruiting
65 years and older
All
Phase N/A

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Overview

The purpose of this pilot study is to assess the feasibility of delivering a multicomponent prehabilitation and measuring patient-centered outcomes in older adults undergoing major surgery.

Description

We will assess the feasibility of delivering a multicomponent prehabilitation, which consists of exercise (supervised by physical therapist), nutritional intervention (nutritional supplement and group education), meditation (group class), and cognitive behavioral intervention over 3-4 weeks before major elective abdominal, gynecological oncologic, urologic surgery, and cardiovascular procedures. We will also measure patient-centered outcomes (Patient-Reported Outcomes Measurement Information System) at 30 and 90 days after surgery. The target enrollment is 30 patients.

Eligibility

Inclusion Criteria:

  • Patient is scheduled to have a gastrointestinal, gynecological oncologic, urologic, and cardiovascular procedure
  • Patient's frailty index is ≥0.25
  • Patient provides an informed e-consent or remote consent

Exclusion Criteria:

  • Surgery is scheduled less than 21 days
  • Patient is considered an inappropriate candidate per the surgeon's assessment
  • Non-English speaking
  • Patient has a major cognitive impairment confirmed by telephone Montreal Cognitive Assessment (MoCA) <18 or Brief Capacity Assessment Questionnaire
  • Patients with chronic kidney disease stage 3 or higher will be excluded from nutrition intervention of the Prehabilitation intervention bundle.

Study details
    Frailty

NCT05752474

Beth Israel Deaconess Medical Center

12 December 2025

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