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E-cigarettes for Harm Reduction Among Smokers With Serious Mental Illness

E-cigarettes for Harm Reduction Among Smokers With Serious Mental Illness

Recruiting
21 years and older
All
Phase N/A

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Overview

In this open-label, randomized controlled trial study, participants who smoke combustible cigarettes (CC) and are diagnosed with Serious Mental Illness (SMI) will be randomized in two arms to receive harm-reduction counseling and Ecological Momentary Intervention text messaging (EMI) along with either e-cigarettes (EC) or nicotine replacement therapy (NRT) such as patch and lozenges to compare the efficacy in CC smoking reduction.

Eligibility

Inclusion Criteria:

  • Currently smokes 5 or more CPD
  • Willingness and ability to provide informed consent
  • Age of at least 21 years
  • Has SMI diagnosis (such as Schizophrenia, Schizoaffective disorders, Bipolar disorder, Depressive disorders, Trauma and stressor related disorders etc.) as determined using the MINI tool
  • Interested in reducing CC smoking but not necessarily trying to quit
  • Own a mobile phone or have regular access to a mobile phone
  • Able to provide an additional contact to improve follow-up rates

Exclusion Criteria:

  • Is pregnant or breastfeeding
  • Used tobacco other than CC in the past 2 weeks (e.g., EC, cigarillo)
  • Currently engaged in an attempt to quit CC
  • Change in dose of their psychotropic medication(s) in the last 30 days
  • Meeting DSM-V criteria for current alcohol or substance use disorder except for nicotine use disorder and active mild alcohol or substance use disorders.
  • Past month suicidal ideation/suicide attempt and/or psychiatric hospitalization in the last 30 days

Study details
    Cigarette Smoking

NCT05815199

NYU Langone Health

15 February 2024

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