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Cohort Study of Clinical and Neuroimaging Characteristics for BPPV Patients in China

Cohort Study of Clinical and Neuroimaging Characteristics for BPPV Patients in China

Recruiting
18-60 years
All
Phase N/A

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Overview

The main objective is to analyze the abnormality of physical condition, mental health and blood examination of the patients with benign paroxysmal positional vertigo (BPPV). Besides, the investigators aim to establish a database of BPPV based on multimodal magnetic resonance imaging data in the brain to identify high-risk patients with residual dizziness (RD) and systematically establish the comprehensive assessment system for the precise diagnosis, treatment and recovery of RD, optimize the tactics of BPPV management in China.

Description

This is an observational, longitudinal, and single-center study. Confirmed BPPV cases will complete the following programs before and after 1 and 6 months of treatment for exploring biological mechanism and predictive biomarkers of BPPV: 1) fill in the behavioral psychological scales, 2) submit blood samples at a local laboratory, 3) receive 3 times brain MRI scan. The healthy controls will complete the same programs as BPPV-group mentioned above only at the time of inclusion. The investigators will establish the brain MRI database containing neuropsychological scales and blood parameters of BPPV in China.

Eligibility

Inclusion Criteria:

  • Confirmed diagnosis of BPPV/Healthy subjects who have not had BPPV

Exclusion Criteria:

  • History of organic diseases in central nervous system and mental disorder, such as tumors, infections, depressive disorder, schizophrenia, etc. Claustrophobic

Study details
    BPPV
    Vertigo
    Vertigo
    Peripheral

NCT06228196

First Affiliated Hospital Xi'an Jiaotong University

8 March 2024

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