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The Effects of tDCS Combined With rTMS on Post-stroke Cognitive Impairment

The Effects of tDCS Combined With rTMS on Post-stroke Cognitive Impairment

Recruiting
30-80 years
All
Phase N/A

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Overview

If there is a comparison group: Researchers will compare [insert groups] to see if [insert effects]

The purpose of the clinical trial is to find a treatment for stroke patients with cognitive impairment, and the main questions it aims to answer are:

  • [Search for effective treatments of cognitive impairment after stroke]
  • [Explore brain network features with functional near-infrared spectroscopy] Participants will receive conventional treatment, tDCS treatment, or rTMS treatment, or tDCS-rTMS treatment.

And then compare cognitive function and brain function.

Eligibility

Inclusion Criteria:

  • Meet the clinical diagnostic criteria of the Expert Consensus on the Management of Cognitive Impairment after Stroke in 2021;
  • 30-80 years old, right-handed, unilateral hemiplegia;
  • Verbal expression can cooperate with the completion of the evaluation, sustained attention time is longer than 5 minutes;
  • Simple Mental State Examination Scale (MMSE) score ≤26 points; MoCA scale score < 26 points; Memory test (RMBT) score less than 21 points;
  • patients or their family agree to sign the informed consent;
  • The Ethics Committee approved the trial.

Exclusion Criteria:

  • Memory dysfunction caused by other diseases, such as Alzheimer's disease, lewy body dementia, pituitary tumor surgery, hypothyroidism, etc.;
  • There are contraindications of rTMS and tDCS for untreated intracranial aneurysms, severe epilepsy, intracranial metal, etc.
  • Patients with severe visual, cognitive or speech impairment who cannot cooperate with treatment;
  • The condition is not stable; Or other serious physical diseases.

Study details
    Stroke

NCT06252987

The Second Affiliated Hospital of Dalian Medical University

20 February 2024

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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