Image

Efficacy of Thumb-tack Needle Treatment for Diminished Ovarian Reserve

Recruiting
18 - 39 years of age
Female
Phase N/A

Powered by AI

Overview

Diminished Ovarian Reserve (DOR) is characterized as an important cause of infertility. Acupuncture has been extensively used to treat female infertility. This study was conducted to investigate the efficacy of thumb-tack needle,as a new special type of acupuncture and long-lasting treatment modality,in the treatment of DOR.

Description

There will be a multi-center, randomized, sham-controlled trial. 106 patients will be randomly assigned into thumb-tack needle acupuncture or sham-acupuncture in 1:1 ratio. All the patents will achieve 12 sessions of verum or sham treatments in 20 weeks(12 weeks for treatment and 8 weeks for follow-up). Patients, outcome assessors and statisticians are masked from group assignment. The study is aim to evaluate the efficacy of thumb-tack needle for DOR.

Eligibility

Inclusion Criteria:

  • 18 years old ≤ age < 40 years old, female;
  • Clinical diagnosis of Diminished Ovarian Reserve: meet both items in twice tests with an interval of at least 4 weeks(tested between 2rd to 4th day of menstrual cycle):
    1. 10 IU/L < FSH < 20 IU/L,
    2. Anti-Müllerian hormone(AMH) < 1.1ng/mL.
  • without any mind disease, willing to participate in the study and sign the informed

    consent.

  • without any other treatment.

Exclusion Criteria:

  • Low or no response to exogenous gonadotropins, or with congenital anomalies in the development of the reproductive tract;
  • Pregnant or breastfeeding;
  • Abnormal body temperatures at the moment;
  • Psychopath, alcoholic, Patient with severe depression, history of substance abuse and severe primary diseases of cardiovascular, liver, kidney and hematopoietic system;
  • Currently enrolled in other clinical trials or refuse to cooperate with the study protocol.

Study details

Diminished Ovarian Reserve

NCT06223178

Xiaomei Shao

18 February 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.