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Respiratory Muscle Fatigue and Lower Extremity Muscle Oxygenation

Respiratory Muscle Fatigue and Lower Extremity Muscle Oxygenation

Recruiting
18-75 years
All
Phase N/A

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Overview

In our study, changes in vastus lateralis muscle oxygenation will be evaluated with the Moxy device, a functional infrared oxygen measurement device, during the inspiratory muscle fatigue protocol in COPD cases and the healthy control group.

Eligibility

Inclusion Criteria:

  • Having a diagnosis of Stage 2-3 COPD according to the following clinical diagnostic criteria according to the American Thoracic and European Respiratory Societies (ATS-ERS).
  • Having been using the same medications for the last 4 weeks

Exclusion Criteria:

  • Patients with severe comorbid diseases, unstable coronary artery disease, collagen vascular diseases and requiring high-flow oxygen therapy (˃ 3-4 L\min).
  • Presence of any vascular problem that may affect lower extremity muscle oxygenation
  • Presence of another respiratory system disease other than COPD
  • Patients who have had an acute COPD exacerbation in the last 4 weeks
  • Patients experiencing COPD exacerbations during the study protocol
  • Presence of fatty tissue or scar tissue at the measurement points, which may impair the measurement quality.
  • Have already participated in another clinical trial within the last 30 days that may affect the results of the study.

Inclusion Criteria for Healthy Cases

  • Being over 18 years of age
  • Not having any diagnosed chronic disease
  • Not being a smoker

Study details
    COPD

NCT06217276

Istanbul Medipol University Hospital

13 May 2025

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