Overview
The purpose of this study is to assess feasibility, acceptability, and safety of providing transcranial direct current stimulation( tDCS) to Huntingtons Disease (HD) patients in the early to middle stages and to assess the efficacy of tDCS for HD-related behavioral, cognitive and other symptoms
Eligibility
- Participant
Inclusion Criteria:
- confirmed HD mutation carriers
- early (stages 1 and 2) or moderate (stage 3) stages according to Shoulson-Fahn
- exhibit mild to moderate behavioral symptoms, such as clinically diagnosed apathy, irritability, anxiety, depression, aggression and repetition
- stable doses of medications for at least one month
Exclusion Criteria:
- unstable medical conditions
- history of epilepsy
- metallic objects in the brain
- clinical diagnosis of major cognitive disorder or dementia
- Have risk of suicidal behavior, defined as any suicidal behavior or suicidal ideation
of type 4
- Caregiver
Inclusion Criteria:
-willingness to participate in the study
Exclusion Criteria:
-motor/cognitive symptoms related to Alzheimer's disease or Huntington's disease that might
impair the ability to assist the participant during the research study.