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Integrated PET/MRI and Germline Variants to Differentiate Brain Tumopr Recurrence From Iatrogenicchanges in Children

Integrated PET/MRI and Germline Variants to Differentiate Brain Tumopr Recurrence From Iatrogenicchanges in Children

Recruiting
18 years and younger
All
Phase N/A
  • Technical (Original)
  • Simplified (AI rewritten)

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Overview

Nuclear magnetic resonance imaging (NMR) is used in pediatric brain tumors for purposes of diagnosis, evaluation of response to treatments, and monitoring of patients in follow-up. Through conventional imaging techniques it remains difficult to differentiate tumor recurrence from pseudo-progression or other iatrogenic changes after radiotherapy or chemotherapy, but it remains a relevant and essential clinical need for patient management.

Eligibility

Inclusion Criteria:

  • children and/or adolescents (≤18 years) diagnosed with brain tumor.
  • children who underwent the contemporary adjuvant therapy protocol of post-surgical chemo and radiotherapy.

Exclusion Criteria:

  • patients >18 years

Study details
    Pediatric Brain Tumor

NCT06226519

IRCCS San Raffaele

29 January 2024

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